Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles
نویسندگان
چکیده
منابع مشابه
Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles
The high aqueous solubility, poor permeability, and absorption of berberine (BBR) result in its low plasma level after oral administration, which greatly limits its clinical application. BBR solid lipid nanoparticles (SLNs) were prepared to achieve improved bioavailability and prolonged effect. Developed SLNs showed homogeneous spherical shapes, small size (76.8 nm), zeta potential (7.87 mV), e...
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ژورنال
عنوان ژورنال: International Journal of Nanomedicine
سال: 2013
ISSN: 1178-2013
DOI: 10.2147/ijn.s51262